Magic Mushrooms, LSD, Hallucinogenic plants, MicroDosing
An under-the-radar company has made enough of the active ingredient in magic mushrooms to send 20,000 people on a trip.
Compass Pathways, which is based in London and boasts an advisory board of esteemed scientists, is cranking out psilocybin to study the compound in people with depression.
That work comes amid a recent resurgence in the study of psychedelic drugs like mushrooms and LSD for mental illness. While most of the research is being led by universities and non-profit research institutions, Compass, a for-profit company founded in 2016, sees itself as helping to fill in the gaps.
The startup has attracted funding from big names like Peter Thiel. London-based entrepreneur Christian Angermayer, ex-hedge fund manager Mike Novogratz, and film producer Sam Englebardt.
Compass has also secured scientific oversight from respected researchers like Tom Insel, the former director of the National Institutes of Mental Health, and David Nutt, the former UK government drug czar, who serve on its board of advisors.
So far, Compass claims it has made two 250-gram batches of psilocybin, the equivalent of 20,000 doses of 25 mg of the drug. Although some of that will be tested for stability, the rest has been shaped into capsules. Those will soon be shipped to a handful of sites in Europe and North America, where Compass plans to use the psilocybin in clinical trials. Read more: BusinessInsider
D-lysergic acid diethylamide tartarate 25is made from an alkaloid found in rye fungus ergot. It was first synthesized at the Sandoz Laboratories in Switzerland in 1938. No one really knows how acid words, but it opens the conscious mind to all sorts of things from the sub conscious that are normally censored. Sense impressions become more vivid and "sense-swapping" often happen-seeing sounds or tasting colors. Mental clarity and a oneness with the environment are common effects. Muscular coordination and pain perception are reduced, and if hallucinations occur, they often involve color and shape patterns-colors become vivid and often pulsate and swirl. The main effects of acid are psychological and therefore nearly impossible to describe. LSD hallucinations are pleasant and the user knows that they are hallucinating unlike other drug hallucinations (Crystal meth/DMT)
As to bad or good trips, there seems to be little middle ground when real LSD is used (it is a fallacy that acid is easy to make) so the bad trips may be results of adulterated acid-not LSD at all, but some related drug. As far as anyone knows, there is no lethal dose of acid. The usual amount is 50 to 150 micrograms (even though dealers claim you are getting from 250 to 1000 mikes). Acid is usually taken orally in tablets, though it sometimes is injected. Chemical dangers are not in evidence. The great chromosome damage scare was pretty much a put-on.
Acid will break your chromosomes, but so do many other things (aspirin, for instance). The real danger is to your mind and controlling yourself when tripping. Latent psychosis may be triggered and previous ways of life may seem unacceptable. How you handle yourself with "new revelations" or surfacing, sub-conscious thoughts and relate them to your lifestyle is important. Street price are generally $10 to $12 a hit. The pills that doctors prescribe kill hundreds of people a year while acid/LSD has never killed anyone, yet LSD is illegal.
Acid will take effect from 1/2 to 2 hours after dropping itand will last 3 to 12 hours. Sometime you get "flashbacks"-short periods of tripping the next day, or even in the next week or two.
If you've decided to take acid, to reduce the chance of a bad trip, take a friend along who has done it before and find a place where you won't be disturbed for about 8 hours...preferably out-of-doors. Keep away from harsh lights, loud noise and confusion. You can do things normally on acid-you may not feel like you can walk or talk, but give it a try and you'll be surprised how easy it is-just redirect your mind to it. Remember, you don't look conspicuous no matter how extraordinary you feel, and if things start going wrong; don't worry-the drug will wear off and bad trips are NOT caused by drug quality (when real acid is used) but by your mind and environment.
The ATROPA BELLADONNA belongs to the potato family and contains Scopolamine. Scopolamine is a depressant, but toxic doses cause bizarre hallucinations. Average doses are 0.5 to 1.0 milligrams, causing euphoria, and drowsiness. Higher doses (5milligrams or more) cause fatigue, aches, blurred vision, slurred speech and frightening hallucinations. It has very unpleasant toxic effects.
Morning glory seeds
The seeds are brown or black and many times triangular rather than round, as are the non-potent varieties. They are legal-but be careful as the seeds may be coated with dangerous chemicals to prevent spoilage. Popular brands are Pearly White, Pearly Gate, Heavenly Blue and Flying Saucer. Chew, grind up, or soak in water-strain drink the liquid. A large dose will produce similar effects to LSD-each seed is equivalent to microgram. Side effects are nausea, dizziness, diarrhea, thirst and a bitter taste.
When taken in amounts of less than 10 grams, nutmeg causes brief euphoria, lightheadedness, and relaxation. Because it stimulates the central nervous system, it can cause tenseness. Doses in excess of 10 grams cause thirst, anxiety, and sometimes acute pain. Hallucinations are rare and you can get a bad hangover.
By Andrew Leonard
Let's call him "Ken." Ken is 25, has a master's degree from Stanford and works for a tech startup in San Francisco, doing a little bit of everything: hardware and software design, sales and business development. Recently, he has discovered a new way to enhance his productivity and creativity, and it's not Five Hour Energy or meditation.
Ken is one of a growing number of professionals who enjoy taking "microdoses" of psychedelics – in his free time and, occasionally, at the office. "I had an epic time," he says at the end of one such day. "I was making a lot of sales, talking to a lot of people, finding solutions to their technical problems."
A microdose is about a tenth of the normal dose – around 10 micrograms of LSD, or 0.2-0.5 grams of mushrooms. The dose is subperceptual – enough, says Rick Doblin, founder and executive director of the Multidisciplinary Association for Psychedelic Studies, "to feel a little bit of energy lift, a little bit of insight, but not so much that you are tripping."
At a conference on psychedelic research in 2011, James Fadiman, author of The Psychedelic Explorer's Guide, introduced microdosing to the popular discourse when he presented the results of survey data he had collected from self-reporting experimenters. Ever since, he says, the number of people describing their experiences – or asking for advice – has been on a steady rise.
The reports come from all over the world, but Fadiman says there's a steady, consistent stream originating in the San Francisco area. The typical profile there is an "übersmart twentysomething" curious to see whether microdosing will help him or her work through technical problems and become more innovative. "It's an extremely healthy alternative to Adderall," says Fadiman, referring to a drug popular with programmers.
For best results, Fadiman recommends microdosing every fourth day, taking the drug in the morning and then sticking to your usual daily routine. His correspondents have told him regular microdosing has alleviated a bevy of disorders, including depression, migraines and chronic-fatigue syndrome, while increasing outside-the-box thinking. "Microdosing has helped me come up with some new designs to explore and new ways of thinking," Ken says. "You would be surprised at how many people are actually doing it. It's crazy awesome."
From The Archives Issue 1249: December 3, 2015
We help spread accurate information about magic mushrooms so people can make informed decisions about what they put in their bodies. You can learn about the effects of shrooms and read trip reports, find out how to grow mushrooms and get mushroom recipes, browse through the gallery and hang out on our message board, or check out the site map for everything the Shroomery has to offer.
SAMHSA's Center for Substance Abuse Treatment
The Substance Abuse & Mental Health Services Administration can get you in touch with a drug abuse treatment program near you. 800-662-4357
Narcotics Anonymous (NA)
Don't want your information monitored online? Whatever you do, don't Google.
How long will this drug stay in my system? LSD 12 to 24 hours
A drug test is a technical analysis of a biological specimen – for example urine, hair, blood, sweat, or oral fluid / saliva – to determine the presence or absence of specified parent drugs or their metabolites.
Urinalysis is the most common test type and used by federally mandated drug testing programs and is considered the Gold Standard of drug testing.
(How to) Make LSD
(PDF) The DBA has recently estimated the total number of clandestine LSD labs operating in the United States at only 100, with most of them located in northern California.
LSD How to make ACID ABC’s By Michael Valentine Smith Fungi of the genus Claviceps, which grow on rye wheat, rice and other grasses, were the first natural source of these alkaloids to be discovered. In recent years related compounds have been found in the genera Penicillium (the blue-green mold that also produces penicillin), Aspergillus, and Rhizobus (the black bread mold). These compounds are now produced commercially by culturing certain strains of Clavicebs which produce as much as 4 g of ergotamine per Liter of culture medium. Growing pure cultures of fungi is not for amateurs, but those interested will find this useful.
Illegal LSD Production LSD has been manufactured illegally since the 1960’s. A limited number of chemists, probably less than a dozen, are believed to be manufacturing nearly all of the LSD available in the United States. Some of these manufacturers probably have been operating since the 1960’s.
CIA’s Secret LSD Experiments on Americans
By Maia Szalavitz TIME magazine Before LSD escaped the lab and was evangelized by hippies, the U.S. government was secretly testing the effects of the drug on hundreds of unsuspecting American civilians and military personnel. In a must-read feature on newly unclassified material on the Central Intelligence Agency’s covert operation, the MK-ULTRA program, which ran from 1953 to 1964, SF Weekly fully exposes the bizarre world of the CIA’s unethical drug tests. The utterly-unbelievable-but-true story involved using hookers to lure in unwitting johns for undisclosed testing, narcotics agents who slipped drugs into drinks, and a U.S. marshal who held up a San Francisco bar not knowing he was high on acid. Source: TIME
“LSD is a psychedelic drug which occasionally causes psychotic behavior in people who have NOT taken it.”
― Timothy Leary
Reality is just a crutch for people who can't handle drugs.”
― Robin Williams
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